Investigación

PLoS One. 2016 Mar 4;11(3):e0150459. doi: 10.1371/journal.pone.0150459. eCollection 2016. Nitro-Arachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells. Sánchez-Calvo B1, Cassina A1, Rios N1, Peluffo G1, Boggia J2, Radi R1, Rubbo H1, Trostchansky A1.
Free Radic Biol Med. 2016 Jun;95:112-20. doi: 10.1016/j.freeradbiomed.2016.03.013. Epub 2016 Mar 22. Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation. Diaz-Amarilla P1, Miquel E2, Trostchansky A3, Trias E4, Ferreira AM5, Freeman BA6, Cassina…
Impact of SIN-1-derived peroxynitrite flux on endothelial cell redox homeostasis and bioenergetics: protective role of diphenyl diselenide via induction of peroxiredoxins. Fiuza B, Subelzú N, Calcerrada P, Straliotto MR, Piacenza L, Cassina A, Rocha JB, Radi R, de Bem AF, Peluffo G. Free Radic Res. 2015 Feb;49(2):122-32. doi: 10.3109/10715762.2014.983096. Epub…
Insights into the mechanism of the reaction between hydrogen sulfide and peroxynitrite. Cuevasanta E, Zeida A, Carballal S, Wedmann R, Morzan UN, Trujillo M, Radi R, Estrin DA, Filipovic MR, Alvarez B. Free Radic Biol Med. 2015 Mar;80:93-100. doi: 10.1016/j.freeradbiomed.2014.12.017. Epub 2014 Dec 30. PMID: 25555671
Leghemoglobin is nitrated in functional legume nodules in a tyrosine residue within the heme cavity by a nitrite/peroxide-dependent mechanism. Sainz M, Calvo-Begueria L, Pérez-Rontomé C, Wienkoop S, Abián J, Staudinger C, Bartesaghi S,Radi R, Becana M. Plant J. 2015 Mar;81(5):723-35. doi: 10.1111/tpj.12762. PMID: 25603991
Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents. Tovmasyan A, Carballal S, Ghazaryan R, Melikyan L, Weitner T, Maia CG, Reboucas JS, Radi R, Spasojevic I, Benov L, Batinic-Haberle I. I norg Chem. 2014 Nov…
Pulm Pharmacol Ther. 2014 Aug;28(2):122-9. doi: 10.1016/j.pupt.2013.12.005. Epub 2014 Jan 3. Sevoflurane anesthesia deteriorates pulmonary surfactant promoting alveolar collapse in male Sprague-Dawley rats. Malacrida L1, Reta G1, Piriz H1, Rocchiccioli F1, Botti H2, Denicola A3, Briva A4.
J Biol Chem. 2014 May 30;289(22):15536-43. doi: 10.1074/jbc.M113.539213. Epub 2014 Apr 9. Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase. Randall LM1, Manta B2, Hugo M3, Gil M4, Batthyàny C5, Trujillo M3, Poole LB6, Denicola A7.
J Biol Chem. 2014 Feb 21;289(8):5228-39. doi: 10.1074/jbc.M113.510248. Epub 2013 Dec 30. Mycothiol/mycoredoxin 1-dependent reduction of the peroxiredoxin AhpE from Mycobacterium tuberculosis. Hugo M1, Van Laer K, Reyes AM, Vertommen D, Messens J, Radi R, Trujillo M.
Glycobiology. 2014 May;24(5):428-41. doi: 10.1093/glycob/cwu008. Epub 2014 Jan 21. Structural basis of redox-dependent modulation of galectin-1 dynamics and function. Guardia CM1, Caramelo JJ, Trujillo M, Méndez-Huergo SP, Radi R, Estrin DA, Rabinovich GA.
PLoS One. 2014 Jan 14;9(1):e84884. doi: 10.1371/journal.pone.0084884. eCollection 2014. Olives and olive oil are sources of electrophilic fatty acid nitroalkenes. Fazzari M1, Trostchansky A2, Schopfer FJ3, Salvatore SR3, Sánchez-Calvo B4, Vitturi D3, Valderrama R4, Barroso JB4, Radi R2, Freeman BA3, Rubbo H2.
Chem Commun (Camb). 2014 Mar 11;50(20):2592-4. doi: 10.1039/c3cc47207h. Coupling of tyrosine deprotonation and axial ligand exchange in nitrocytochrome c. Capdevila DA1, Álvarez-Paggi D, Castro MA, Tórtora V, Demicheli V, Estrín DA, Radi R, Murgida DH.
Free Radic Biol Med. 2014 May;70:204-13. doi: 10.1016/j.freeradbiomed.2014.02.019. Epub 2014 Feb 26. Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis. Miquel E1, Cassina A2, Martínez-Palma L1, Souza JM2, Bolatto C1, Rodríguez-Bottero S1, Logan A3, Smith RA4, Murphy MP3, Barbeito L5, Radi R2, Cassina…
Free Radic Res. 2014 Jun;48(6):684-93. doi: 10.3109/10715762.2014.900175. Epub 2014 Apr 1. Metabolic control analysis of mitochondrial aconitase: influence over respiration and mitochondrial superoxide and hydrogen peroxide production. Scandroglio F1, Tórtora V, Radi R, Castro L
J Biol Chem. 2014 May 2;289(18):12760-78. doi: 10.1074/jbc.M113.545590. Epub 2014 Mar 10. Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolecular electron transfer. Martinez A1, …
Free Radic Biol Med. 2014 Aug;73:421-9. doi: 10.1016/j.freeradbiomed.2014.05.021. Epub 2014 Jun 2. Neurovascular coupling in hippocampus is mediated via diffusion by neuronal-derived nitric oxide. Lourenço CF1, Santos RM1, Barbosa RM1, Cadenas E2, Radi R3, Laranjinha J4.
Redox Rep. 2014 Nov;19(6):221-31. doi: 10.1179/1351000214Y.0000000099. Epub 2014 Jun 30. Metal-catalyzed protein tyrosine nitration in biological systems. Campolo N, Bartesaghi S, Radi R
Chem Commun (Camb). 2014 Sep 11;50(70):10070-3. doi: 10.1039/c4cc02899f. The extraordinary catalytic ability of peroxiredoxins: a combined experimental and QM/MM study on the fast thiol oxidation step. Zeida A1, Reyes AM, Lebrero MC, Radi R, Trujillo M, Estrin DA.
Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis Ernesto Miquela, Adriana Cassinab, c, Laura Martínez-Palmaa, José M. Souzab, c, Carmen Bolattoa, Sebastián Rodríguez-Botteroa, Angela Logand, Robin A.J. Smithe, Michael P. Murphyd, Luis Barbeitof, Rafael Radib, c, Patricia Cassinaa, c.
Nitrogen dioxide solubility and permeation in lipid membranes. Signorelli S, Möller MN, Coitiño EL, Denicola A. Arch Biochem Biophys. 2011 Aug 15;512(2):190-6. doi: 10.1016/j.abb.2011.06.003. Epub 2011 Jun 15.
Página 1 de 2